Hive Networks powers Learning Health Networks across rare disease, pediatric health, oncology, and mental health — enabling patients, clinicians, and researchers to collaborate, share evidence, and continuously improve care.
ImproveCareNow (ICN) is the world's largest and fastest-growing pediatric IBD learning health network, dedicated to improving the health and care of children and youth with Crohn's disease and ulcerative colitis. Through unprecedented collaboration among patients, families, clinicians, and researchers, ICN has become one of the most effective improvement science initiatives in pediatric healthcare.
In 2020, Hive Networks announced a multi-year partnership with ImproveCareNow to add capacity to its Learning Health Network infrastructure. Hive provides a software platform enabling peer-to-peer sharing of data, knowledge, and expertise — alongside consulting services supporting community formation and growth. The platform integrates social, organizational, improvement, and data sciences to empower patients as active stakeholders in treatment development.
"Hive will enable our community to better cross-pollinate ideas, deliver data more efficiently, and connect our members to major research initiatives aimed at curing chronic disease."
Non-hierarchical platform empowering patients, clinicians, and researchers as equal collaborators in continuous improvement.
The largest and fastest-growing pediatric IBD registry worldwide — powering quality improvement and research at every participating center.
Efficient data delivery among collaborators, enabling real-time performance benchmarking across the network's 100+ care centers.
Platform connects network participants to major research initiatives aimed at discovering cures for pediatric inflammatory bowel disease.
Patients and parent/family advisory councils co-govern the network, ensuring lived experience shapes every improvement initiative.
Structured quality improvement methodology with SPC charts, run charts, and PDSA cycles — embedded in the platform workflow.
PEDSnet is a national pediatric Learning Health System (LHS) established in 2013, connecting children's hospitals across the United States to accelerate child health research. Part of the Patient Centered Outcomes Research Network (PCORnet), PEDSnet has standardized electronic health record data from more than 14 million children — creating one of the most powerful pediatric research infrastructures in the world.
PEDSnet's OMOP-based common data model is one of the key source systems that Hive Networks' next-generation platform is built to integrate with — with a proven 8–10 week migration pathway. Hive's federated data fabric preserves PEDSnet's institutional data sovereignty model while adding an AI and clinical decision support layer on top of the existing OMOP infrastructure. The result: PEDSnet's 14+ million patient records become accessible for real-time clinical decision support and federated learning, without any raw data movement between institutions.
PEDSnet's CDM is based on OMOP, extended with pediatric-specific fields and tables. Hive's FHIR R4 ingestion layer maps directly from OMOP in 8–10 weeks.
PEDSnet supports distributed queries — the same privacy-preserving model Hive's federated data fabric uses to enable cross-institutional analysis without data movement.
Over a fifth of PEDSnet's 371 published studies relate to COVID-19 — demonstrating the network's capacity for urgent, large-scale evaluation that Hive's AI layer can accelerate further.
Founded in 2019 in response to the urgent need for improvements in pancreatic cancer survival, Canopy Cancer Collective connects 14+ leading cancer centers in a learning health network that shares data and best practices to accelerate improvements in pancreatic cancer care delivery and outcomes. The network's mission is to transform outcomes in pancreas and gastrointestinal cancers through bold innovation and relentless collaboration in research and whole-person care.
Canopy Cancer Collective operates as a learning health network — the same model that Hive Networks was purpose-built to support. Hive's acquisition by Vora Ventures was specifically motivated by expanding its reach into rare and serious disease outcomes, including oncology. The Hive platform provides the collaboration infrastructure, data-sharing backbone, and improvement science tools that enable Canopy's 14 cancer centers to act as a unified learning community — tracking every pancreatic cancer patient in real time, ensuring access to genetic testing, nutritional support, and clinical trial enrollment. Hive's oncology-grade data architecture, aligned to the mCODE standard, supports Canopy's Clinical Quality Improvement Database and its ongoing publication of early network results in the Journal of Clinical Oncology.
Clinical Quality Improvement Database enables real-time tracking of every pancreatic cancer patient — ensuring genetic testing, nutritional support, and trial access at diagnosis.
Platform coordinates care and learning among surgeons, oncologists, scientists, and wellness specialists across institutions — enabling true whole-person care.
Network infrastructure connects patients to clinical trials across all 14 member institutions — dramatically increasing trial eligibility identification and enrollment speed.
The Bipolar Action Network (BAN) is a collaborative learning health network with a vision to enhance the health and well-being of every person living with bipolar disorder. Through unprecedented collaboration powered by breakthrough data sharing and unwavering empathy, BAN engages patients, families, clinicians, and researchers to co-develop solutions — bridging the gap between research and clinical practice for one of psychiatry's most complex and undertreated conditions.
The Bipolar Action Network runs directly on the Hive Networks platform — accessible to members at ban.hivenetworks.com. Hive provides the full Learning Health Network infrastructure: member portal, data sharing tools, collaborative workspace, and community engagement features. In 2024, BAN convened in Boston to address critical challenges including establishing systematic approaches to decrease death by suicide — using Hive's collaborative platform to coordinate improvement work across its 18 member healthcare systems. The network is a published example of how the Hive Learning Health Network model applies to mental health, with results published in peer-reviewed journals including Bipolar Disorders and Psychiatric Annals.
"Hive applies its Learning Health Network model to mental health — working with the Bipolar Action Network to improve care for individuals with bipolar disorder through collaborative data analysis and shared learning among clinicians, researchers, and patients."
Dedicated Hive-powered member portal provides secure access to collaborative tools, shared resources, network data, and community discussions for BAN participants.
Systematic approaches to reducing diagnostic delay in bipolar disorder — a condition with an average 6–10 year gap between symptom onset and correct diagnosis.
In 2024, BAN formalized a network-wide initiative to decrease death by suicide — using Hive's improvement science infrastructure to coordinate interventions across 18 healthcare systems.
Whether you're launching a new LHN or looking to add AI and data infrastructure to an existing collaborative, Hive Networks provides the platform, expertise, and community to accelerate your mission.